Chemical and Pharmaceutical

Hycontrol has extensive experience in the Chemical and Pharmaceutical sector, dealing with a range of applications. Common applications in this sector include:

  • Silo protection
  • Liquid level measurement and overfill prevention for products including:
    • Caustic acids
    • Soaps
    • Hydrochloric acids
    • TDI (toluene)
    • Waste products and effluent
  • Corrosive applications
  • ATEX-approved equipment
  • Foam level monitoring and control

 

Application: Pharmaceutical Foam Control

The development and production of pharmaceutical products frequently involve mixing liquids and adding air or other gases. This is particularly the case for fermentation processes which are increasingly used to produce precursors and end products. Foam is a common problem in fermentation processes and can cause overflows, blocked filters, contamination, damage to equipment and expensive complete product loss.A common way to control foam is by continuous or manual addition of defoamer chemicals. This is hit-and-miss, with considerable disadvantages. It is almost impossible to add the optimum amount of antifoam without measuring the foam. Overdosing with antifoam reduces the mass gas transfer and consequently reduces the efficiency and yield of the process.

By far the best approach to managing foam in a bioreactor is to measure the foam using a foam sensor fitted in the head plate and to add just enough defoamer only when it is required. Hycontrol's foam sensors were originally designed for just this purpose. Hycontrol has many years of experience with measuring foam in fermenters and bioreactors using microbial, animal cell, fungal and other microorganisms. We can provide products to USP Class 6 standards with the required documentation using FDA approved materials. There is a wide range of available fittings to suit all makes of vessels including laboratory scale, pilot scale and production scale bioreactors. Hycontrol foam sensors are hygienic, steam sterilizing and suitable for CIP. The sensors are designed with fouling immunity to prevent false alarms and overdosing. Additionally, they can be used to measure both liquid and foam level at the same time. This is particularly useful in busy reactors with limited head plate ports. 

 

We are proud to include Basildon Chemicals, Bituchem, Corus, Bayer & Bayer, Colgate, CaligenBASF, Monarch Chemicals and GSK amongst our customers in this sector. To discuss your requirements further, please contact us.

Digester Foam Control Application - Tata Chemicals (India)
Phosphoric Acid Level Control with 80 GHz Radar Application - Chemical Manufacturer
Silo Protection System Installation Application - Sika
Waste Water Foam Monitoring & Control Application - Monarch Chemicals
Corrosive Chemical Level Monitoring Application - F2 Chemicals
Chemical Storage Ultrasonic Level Application - Outokumpu
ATEX Level Monitoring & Multi-Point Display Application - Centec
Adhesive Level Measurement & Overfill Protection Application - Bostik
ATEX Chemical Level Measurement & Overfill Protection Application - Tremco Illbruck
High-Accuracy ATEX Level Measurement Application - Caldic
Non-Invasive TDR Level Measurement Application - Premiere Products

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